C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006911 Cdk4-001 ENSMUSG00000006728 10090 + 10:127063534-127067920 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverOvaryPlacentaTestisENSMUST00000006911
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENSMUST00000006911 22.500±1.03 16.537±2.30 34.995±12.19 10.578±0.78 16.135±2.22 12.108±0.00 28.823±11.22 25.141±1.53 27.961±4.86 3.549±0.37

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000307 IPI cyclin-dependent protein kinase holoenzyme complex
GO:0000785 IEA chromatin
GO:0002088 IEA lens development in camera-type eye
GO:0004672 IDA protein kinase activity
GO:0004693 IDA cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005730 IEA nucleolus
GO:0005829 IEA cytosol
GO:0005923 IDA tight junction
GO:0006468 IDA protein phosphorylation
GO:0007165 IDA signal transduction
GO:0007623 IEA circadian rhythm
GO:0008284 IEA positive regulation of cell proliferation
GO:0009636 IEA response to toxic substance
GO:0010033 IEA response to organic substance
GO:0010288 IEA response to lead ion
GO:0010468 IEA regulation of gene expression
GO:0010971 ISS positive regulation of G2/M transition of mitotic cell cycle
GO:0016301 IDA kinase activity
GO:0030332 IEA cyclin binding
GO:0031100 IEA organ regeneration
GO:0031965 IEA nuclear membrane
GO:0032403 IEA protein complex binding
GO:0033574 IEA response to testosterone
GO:0042127 IMP regulation of cell proliferation
GO:0042493 IEA response to drug
GO:0043065 IEA positive regulation of apoptotic process
GO:0045727 IEA positive regulation of translation
GO:0045793 IEA positive regulation of cell size
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051301 IEA cell division
GO:0051726 IDA regulation of cell cycle
GO:0055093 IEA response to hyperoxia
GO:0071157 ISS negative regulation of cell cycle arrest

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000257904 CDK4-001 protein_coding Homo_sapiens 0 1321
ENST00000312990 CDK4-201 protein_coding Homo_sapiens 0 473
ENST00000546489 CDK4-007 protein_coding Homo_sapiens 0 758
ENST00000547281 CDK4-009 protein_coding Homo_sapiens 0 878
ENST00000547992 TSPAN31-002 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000549606 CDK4-004 protein_coding Homo_sapiens 0 324
ENST00000550419 CDK4-008 nonsense_mediated_decay Homo_sapiens 0 688
ENST00000551706 CDK4-002 retained_intron Homo_sapiens 0 472
ENST00000551800 CDK4-005 protein_coding Homo_sapiens 0 736
ENST00000551888 CDK4-013 processed_transcript Homo_sapiens 0 475
ENST00000552254 CDK4-011 protein_coding Homo_sapiens 0 745
ENST00000552388 CDK4-006 protein_coding Homo_sapiens 0 678
ENST00000552713 CDK4-014 retained_intron Homo_sapiens 0 324
ENST00000552862 CDK4-012 protein_coding Homo_sapiens 0 433
ENST00000553237 CDK4-003 nonsense_mediated_decay Homo_sapiens 0 673

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