C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: profilin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018437 Pfn1-001 ENSMUSG00000018293 10090 - 11:70651850-70654644 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018437
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018437 423.009±78.06 843.288±258.90 698.872±8.08 135.595±70.52 864.353±423.56 1336.212±153.93 176.106±33.81 314.712±27.67 352.284±107.54 466.238±126.02 153.817±17.72 925.451±380.41 506.645±326.00 54.944±30.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000C6 CIL_0000C6_0002 CGP 11:70647235-70654644
CIL_000060 CIL_000060_0002 CGP 11:70651850-70662513

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000774 IEA adenyl-nucleotide exchange factor activity
GO:0001843 IGI neural tube closure
GO:0003779 IEA actin binding
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005546 IEA phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005925 IEA focal adhesion
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0008064 TAS regulation of actin polymerization or depolymerization
GO:0010033 IEA response to organic substance
GO:0010634 IEA positive regulation of epithelial cell migration
GO:0016020 IEA membrane
GO:0017048 IPI Rho GTPase binding
GO:0030036 IEA actin cytoskeleton organization
GO:0030837 IEA negative regulation of actin filament polymerization
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0032232 IEA negative regulation of actin filament bundle assembly
GO:0032781 IEA positive regulation of ATPase activity
GO:0042989 TAS sequestering of actin monomers
GO:0043005 IEA neuron projection
GO:0044822 IEA poly(A) RNA binding
GO:0045202 IEA synapse
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050434 IEA positive regulation of viral transcription
GO:0051054 IEA positive regulation of DNA metabolic process
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0051497 IEA negative regulation of stress fiber assembly
GO:0070062 IEA extracellular vesicular exosome
GO:0070064 IEA proline-rich region binding
GO:0071363 IEA cellular response to growth factor stimulus
GO:0072562 IEA blood microparticle
GO:1900029 IEA positive regulation of ruffle assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000225655 PFN1-001 protein_coding Homo_sapiens 0 1088
ENST00000434838 NBPF3-003 nonsense_mediated_decay Homo_sapiens 0 281
ENST00000442087 PFN1P1-001 processed_pseudogene Homo_sapiens 0 603
ENST00000445829 PFN1P11-001 processed_pseudogene Homo_sapiens 0 270
ENST00000455938 PFN1P12-001 processed_pseudogene Homo_sapiens 0 399
ENST00000455962 PFN1P10-001 processed_pseudogene Homo_sapiens 0 348
ENST00000497012 PFN1P8-001 processed_pseudogene Homo_sapiens 0 512
ENST00000519266 ENO3-007 protein_coding Homo_sapiens 4e-27 124
ENST00000520221 ENO3-019 protein_coding Homo_sapiens 7e-38 161
ENST00000572383 PFN1-003 protein_coding Homo_sapiens 0 558
ENST00000574872 PFN1-002 protein_coding Homo_sapiens 0 702
ENST00000604437 PFN1P2-002 processed_transcript Homo_sapiens 0 586

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