C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020340 Pcsk4-001 ENSMUSG00000020131 10090 - 10:80321283-80329498 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonLiverLungOvaryPlacentaTestisENSMUST00000020340
Transcript ID Bladder Brain Colon Liver Lung Ovary Placenta Testis
ENSMUST00000020340 0.414±0.10 0.202±0.02 1.521±0.43 0.740±0.22 0.703±0.00 1.020±0.08 0.300±0.00 68.386±30.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZH CIL_0000ZH_0002 CGP 10:80318254-80329498
CIL_00066P CIL_00066P_0002 CGP 10:80321283-80336441

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002080 IDA acrosomal membrane
GO:0004252 IBA serine-type endopeptidase activity
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006508 IBA proteolysis
GO:0007339 IMP binding of sperm to zona pellucida
GO:0007340 IMP acrosome reaction
GO:0009566 IMP fertilization
GO:0048240 IMP sperm capacitation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000300954 PCSK4-001 protein_coding Homo_sapiens 0 1594
ENST00000441747 PCSK4-003 retained_intron Homo_sapiens 0 824
ENST00000586616 PCSK4-002 retained_intron Homo_sapiens 3.00018e-42 178
ENST00000588195 PCSK4-006 retained_intron Homo_sapiens 0 878
ENST00000591201 PCSK4-004 nonsense_mediated_decay Homo_sapiens 0 782
ENST00000591303 PCSK4-012 retained_intron Homo_sapiens 0 339

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