C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: proprotein convertase subtilisin/kexin type 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000300954 PCSK4-001 ENSG00000115257 9606 - 19:1481428-1490408 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLungTestisENST00000300954
Transcript ID Brain Lung Testis
ENST00000300954 1.388±0.00 1.040±0.00 34.051±4.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZH CIL_0000ZH_0001 CGP 19:1461143-1490752
CIL_00066P CIL_00066P_0001 CGP 19:1481428-1497927

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002080 IEA acrosomal membrane
GO:0004252 IBA:IEA serine-type endopeptidase activity
GO:0006508 IBA:IEA proteolysis
GO:0007339 IEA binding of sperm to zona pellucida
GO:0007340 IEA acrosome reaction
GO:0009566 IEA fertilization
GO:0016021 IEA integral component of membrane
GO:0048240 IEA sperm capacitation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020340 Pcsk4-001 protein_coding Mus_musculus 0 1594
ENSMUST00000137177 Pcsk4-004 retained_intron Mus_musculus 0 1086
ENSMUST00000135071 Pcsk4-003 nonsense_mediated_decay Mus_musculus 0 1051
ENSMUST00000128653 Pcsk4-002 nonsense_mediated_decay Mus_musculus 0 974
ENSDART00000104629 furinb-001 protein_coding Danio_rerio 0 309
ENSMUST00000130521 Pcsk4-006 retained_intron Mus_musculus 6e-34 150
ENSMUST00000147132 Pcsk4-005 retained_intron Mus_musculus 6e-34 150

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