C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transformed mouse 3T3 cell double minute 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020408 Mdm2-001 ENSMUSG00000020184 10090 - 10:117688888-117710758 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020408
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020408 8.254±1.50 12.058±2.21 18.195±3.37 10.680±6.13 10.309±4.68 12.626±2.25 8.397±2.70 9.547±1.58 7.248±2.75 14.302±2.02 7.460±1.42 13.877±3.68 18.225±6.13 34.176±13.53

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IPI p53 binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006461 IEA protein complex assembly
GO:0006977 IEA DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007089 IDA traversing start control point of mitotic cell cycle
GO:0009636 IEA response to toxic substance
GO:0009743 IEA response to carbohydrate
GO:0010039 IEA response to iron ion
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0010955 IEA negative regulation of protein processing
GO:0016567 ISS protein ubiquitination
GO:0016604 IEA nuclear body
GO:0016874 IEA ligase activity
GO:0018205 IEA peptidyl-lysine modification
GO:0019899 IEA enzyme binding
GO:0030163 IDA protein catabolic process
GO:0031625 IEA ubiquitin protein ligase binding
GO:0031648 IEA protein destabilization
GO:0032026 IEA response to magnesium ion
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504 IEA protein localization to nucleus
GO:0042176 IEA regulation of protein catabolic process
GO:0042220 IEA response to cocaine
GO:0042493 IEA response to drug
GO:0042787 IEA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042802 IEA identical protein binding
GO:0042975 IEA peroxisome proliferator activated receptor binding
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043234 IEA protein complex
GO:0043278 IEA response to morphine
GO:0043518 IEA negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045184 IEA establishment of protein localization
GO:0045202 IEA synapse
GO:0045472 IEA response to ether
GO:0045787 IGI positive regulation of cell cycle
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0046677 IEA response to antibiotic
GO:0046827 IEA positive regulation of protein export from nucleus
GO:0048545 IEA response to steroid hormone
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071157 IEA negative regulation of cell cycle arrest
GO:0071229 IEA cellular response to acid
GO:0071236 IEA cellular response to antibiotic
GO:0071301 IEA cellular response to vitamin B1
GO:0071310 IEA cellular response to organic substance
GO:0071312 IEA cellular response to alkaloid
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0071391 IEA cellular response to estrogen stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071456 IEA cellular response to hypoxia
GO:0071494 IEA cellular response to UV-C
GO:0097110 IPI scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000258148 MDM2-003 protein_coding Homo_sapiens 0 394
ENST00000258149 MDM2-001 protein_coding Homo_sapiens 0 1206
ENST00000299252 MDM2-006 protein_coding Homo_sapiens 0 211
ENST00000311420 MDM2-010 nonsense_mediated_decay Homo_sapiens 0 219
ENST00000348801 MDM2-009 protein_coding Homo_sapiens 0.000000000000005 86
ENST00000350057 MDM2-033 protein_coding Homo_sapiens 3e-24 117
ENST00000356290 MDM2-201 protein_coding Homo_sapiens 0 222
ENST00000360430 MDM2-008 protein_coding Homo_sapiens 3e-23 113
ENST00000393410 MDM2-004 protein_coding Homo_sapiens 0 211
ENST00000393412 MDM2-202 protein_coding Homo_sapiens 0 219
ENST00000393413 MDM2-032 protein_coding Homo_sapiens 2e-23 113
ENST00000393415 MDM2-022 protein_coding Homo_sapiens 0 510
ENST00000393416 MDM2-013 protein_coding Homo_sapiens 0 224
ENST00000393417 MDM2-002 nonsense_mediated_decay Homo_sapiens 0 219
ENST00000428863 MDM2-203 protein_coding Homo_sapiens 0 503
ENST00000462284 MDM2-204 protein_coding Homo_sapiens 1e-25 124
ENST00000478070 MDM2-011 protein_coding Homo_sapiens 0.000000000000004 86
ENST00000481186 MDM2-007 nonsense_mediated_decay Homo_sapiens 1e-22 111
ENST00000493419 MDM2-015 retained_intron Homo_sapiens 0 363
ENST00000496959 MDM2-005 nonsense_mediated_decay Homo_sapiens 0 213
ENST00000517852 MDM2-019 protein_coding Homo_sapiens 0 211
ENST00000523991 MDM2-016 protein_coding Homo_sapiens 0 222
ENST00000536089 MDM2-031 nonsense_mediated_decay Homo_sapiens 0 211
ENST00000537182 MDM2-030 nonsense_mediated_decay Homo_sapiens 0 211
ENST00000539479 MDM2-012 protein_coding Homo_sapiens 0 577
ENST00000540352 MDM2-028 nonsense_mediated_decay Homo_sapiens 0 486
ENST00000542502 MDM2-029 nonsense_mediated_decay Homo_sapiens 0 213
ENST00000543323 MDM2-023 protein_coding Homo_sapiens 0 222
ENST00000544561 MDM2-026 protein_coding Homo_sapiens 0 244
ENST00000545204 MDM2-024 protein_coding Homo_sapiens 7e-26 121
ENST00000546048 MDM2-027 nonsense_mediated_decay Homo_sapiens 0 211

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