C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MDM2 proto-oncogene, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000462284 MDM2-204 ENSG00000135679 9606 + 12:68808172-68845544 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000462284
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000462284 2.666±0.00 4.253±0.00 2.099±0.35 1.253±0.00 4.156±0.39 6.028±0.00 3.865±0.00 1.854±0.41 4.575±1.65 7.948±0.00 2.959±1.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KM CIL_0002KM_0002 CGP 12:68746106-68850686

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0043066 IEA negative regulation of apoptotic process
GO:0071157 IEA negative regulation of cell cycle arrest

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000132277 Mdm2-004 retained_intron Mus_musculus 1e-25 124
ENSMUST00000155285 Mdm2-003 nonsense_mediated_decay Mus_musculus 1e-25 124
ENSMUST00000105263 Mdm2-002 protein_coding Mus_musculus 1e-25 124
ENSMUST00000020408 Mdm2-001 protein_coding Mus_musculus 1e-25 124

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