C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor binding protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020702 Igfbp3-001 ENSMUSG00000020427 10090 - 11:7206086-7213897 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020702
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020702 58.461±29.50 16.370±5.09 29.691±0.80 6.529±4.35 16.022±3.23 16.548±2.36 11.493±0.39 158.562±13.49 14.782±5.42 28.882±1.52 6.701±0.62 20.128±5.30 12.581±10.45 0.982±0.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WT CIL_0008WT_0002 VISTA 11:6754211-7357799
CIL_0005P5 CIL_0005P5_0003 CGP 11:7197782-7213923
CIL_0000S7 CIL_0000S7_0002 CGP 11:7206086-8664535

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 IGI regulation of cell growth
GO:0001649 IEP osteoblast differentiation
GO:0001933 ISO negative regulation of protein phosphorylation
GO:0001968 IDA fibronectin binding
GO:0005515 IEA protein binding
GO:0005520 IPI insulin-like growth factor binding
GO:0005615 IDA extracellular space
GO:0005634 ISO nucleus
GO:0006468 ISO protein phosphorylation
GO:0008160 ISS protein tyrosine phosphatase activator activity
GO:0008285 IEA negative regulation of cell proliferation
GO:0010906 IGI regulation of glucose metabolic process
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0031994 IEA insulin-like growth factor I binding
GO:0040008 IGI regulation of growth
GO:0043065 ISS positive regulation of apoptotic process
GO:0043085 IEA positive regulation of catalytic activity
GO:0043410 IGI positive regulation of MAPK cascade
GO:0043568 IGI positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044342 IGI type B pancreatic cell proliferation
GO:0045663 ISS positive regulation of myoblast differentiation
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000275521 IGFBP3-001 protein_coding Homo_sapiens 0 913
ENST00000381083 IGFBP3-020 protein_coding Homo_sapiens 0 773
ENST00000381086 IGFBP3-008 protein_coding Homo_sapiens 0 641
ENST00000417621 IGFBP3-019 protein_coding Homo_sapiens 0 492
ENST00000428530 IGFBP3-018 protein_coding Homo_sapiens 0 484
ENST00000448817 IGFBP3-014 protein_coding Homo_sapiens 0 327
ENST00000460209 IGFBP3-017 retained_intron Homo_sapiens 0 219
ENST00000613132 IGFBP3-201 protein_coding Homo_sapiens 0 828
ENST00000615754 IGFBP3-202 protein_coding Homo_sapiens 0 708

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