C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor binding protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000275521 IGFBP3-001 ENSG00000146674 9606 - 7:45912598-45921274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000275521
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000275521 25.729±0.00 12.241±0.00 3.685±0.00 2.105±1.40 29.102±0.00 7.795±0.00 1.683±0.00 42.708±0.00 8.066±0.00 3.962±0.00 2.964±0.00 29.758±1.10 292.858±93.61 6.782±3.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005P5 CIL_0005P5_0002 CGP 7:45888357-45921874
CIL_0000S7 CIL_0000S7_0001 CGP 7:45912245-47582558

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0005515 IPI protein binding
GO:0005520 NAS:IEA insulin-like growth factor binding
GO:0005576 NAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0008160 IDA protein tyrosine phosphatase activator activity
GO:0008285 IGI negative regulation of cell proliferation
GO:0009968 NAS negative regulation of signal transduction
GO:0014912 IDA negative regulation of smooth muscle cell migration
GO:0016942 IC insulin-like growth factor binding protein complex
GO:0031994 IPI insulin-like growth factor I binding
GO:0043065 IMP positive regulation of apoptotic process
GO:0043085 IDA positive regulation of catalytic activity
GO:0044267 TAS cellular protein metabolic process
GO:0045663 IDA positive regulation of myoblast differentiation
GO:0046872 NAS metal ion binding
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020702 Igfbp3-001 protein_coding Mus_musculus 0 913
ENSMUST00000135887 Igfbp3-002 protein_coding Mus_musculus 0 808

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