C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine palmitoyltransferase, long chain base subunit 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021424 Sptlc2-001 ENSMUSG00000021036 10090 - 12:87305058-87388355 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021424
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021424 4.140±0.94 7.748±2.06 6.057±0.10 4.011±1.60 3.133±0.75 8.123±2.38 1.438±0.12 6.715±0.23 1.850±0.75 12.306±0.46 0.602±0.09 6.043±1.72 8.071±2.30 0.707±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00064L CIL_00064L_0003 CGP 12:87278638-87388355
CIL_0004TW CIL_0004TW_0002 CGP 12:87305058-87444017

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004758 IDA serine C-palmitoyltransferase activity
GO:0005739 IDA mitochondrion
GO:0006686 IMP sphingomyelin biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0017059 ISA serine C-palmitoyltransferase complex
GO:0030170 IEA pyridoxal phosphate binding
GO:0046511 IDA sphinganine biosynthetic process
GO:0046512 IMP sphingosine biosynthetic process
GO:0046513 IMP ceramide biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000216484 SPTLC2-001 protein_coding Homo_sapiens 0 2627
ENST00000554365 SPTLC2-004 retained_intron Homo_sapiens 0 566
ENST00000554901 SPTLC2-002 protein_coding Homo_sapiens 0 1541
ENST00000556607 SPTLC2-005 nonsense_mediated_decay Homo_sapiens 0 422
ENST00000557566 SPTLC2-003 retained_intron Homo_sapiens 0 479

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