C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262052 SLC11A2-002 ENSG00000110911 9606 - 12:50985992-51026384 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverLungMuscleOvaryPlacentaENST00000262052
Transcript ID Brain Heart Liver Lung Muscle Ovary Placenta
ENST00000262052 12.629±0.00 0.533±0.00 2.934±0.00 3.830±0.00 0.860±0.00 2.389±1.01 3.091±1.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007B4 CIL_0007B4_0001 CGP 12:50953922-51028566

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEP response to hypoxia
GO:0003032 IEP detection of oxygen
GO:0005215 IEA transporter activity
GO:0005375 IDA copper ion transmembrane transporter activity
GO:0005384 IDA manganese ion transmembrane transporter activity
GO:0005385 IDA zinc ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005773 IMP vacuole
GO:0005802 IDA trans-Golgi network
GO:0005886 IMP plasma membrane
GO:0006810 IEA transport
GO:0006824 IDA cobalt ion transport
GO:0006825 IDA copper ion transport
GO:0006828 IDA manganese ion transport
GO:0006879 TAS cellular iron ion homeostasis
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0009986 IDA cell surface
GO:0010039 IEP response to iron ion
GO:0015086 IDA cadmium ion transmembrane transporter activity
GO:0015087 IDA cobalt ion transmembrane transporter activity
GO:0015093 IDA ferrous iron transmembrane transporter activity
GO:0015094 IDA lead ion transmembrane transporter activity
GO:0015099 IDA nickel cation transmembrane transporter activity
GO:0015100 IDA vanadium ion transmembrane transporter activity
GO:0015295 IDA solute:proton symporter activity
GO:0015675 IDA nickel cation transport
GO:0015676 IDA vanadium ion transport
GO:0015684 IDA ferrous iron transport
GO:0015692 IDA lead ion transport
GO:0016020 IDA:IEA membrane
GO:0016324 IDA apical plasma membrane
GO:0022890 IGI inorganic cation transmembrane transporter activity
GO:0031410 IDA cytoplasmic vesicle
GO:0031902 IDA late endosome membrane
GO:0034599 IDA cellular response to oxidative stress
GO:0035444 IDA nickel cation transmembrane transport
GO:0045177 IDA apical part of cell
GO:0045178 IDA basal part of cell
GO:0048471 IDA perinuclear region of cytoplasm
GO:0055037 IDA recycling endosome
GO:0055085 TAS transmembrane transport
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0070574 IDA cadmium ion transmembrane transport
GO:0070627 IDA ferrous iron import
GO:0070826 IDA paraferritin complex
GO:0071421 IDA manganese ion transmembrane transport
GO:0071577 IDA zinc ion transmembrane transport
GO:0098655 IGI cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000138843 Slc11a2-002 protein_coding Mus_musculus 0 2180
ENSMUST00000023774 Slc11a2-001 protein_coding Mus_musculus 0 1978
ENSMUST00000124324 Slc11a2-009 protein_coding Mus_musculus 0 817
ENSMUST00000140535 Slc11a2-008 retained_intron Mus_musculus 0 784
ENSMUST00000123461 Slc11a2-005 protein_coding Mus_musculus 0 604
ENSMUST00000136168 Slc11a2-004 nonsense_mediated_decay Mus_musculus 0 377
ENSMUST00000154331 Slc11a2-003 protein_coding Mus_musculus 0 243

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