C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: twinfilin, actin-binding protein, homolog 2 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000024047 Twf2-001 ENSMUSG00000023277 10090 + 9:106203108-106215389 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000024047
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000024047 15.893±2.20 28.146±8.47 11.844±1.66 15.105±3.23 19.983±8.62 9.169±1.83 5.587±1.86 7.094±6.33 16.857±1.55 15.205±6.52 20.269±5.49 3.301±1.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NT CIL_0008NT_0002 VISTA 9:106082995-106685663
CIL_00087C CIL_00087C_0002 VISTA 9:106116951-106718793

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003785 IDA actin monomer binding
GO:0005080 ISA protein kinase C binding
GO:0005524 ISA ATP binding
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 ISA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0010592 IEA positive regulation of lamellipodium assembly
GO:0010976 IEA positive regulation of neuron projection development
GO:0030016 IDA myofibril
GO:0030027 IDA lamellipodium
GO:0030030 IEA cell projection organization
GO:0030175 IDA filopodium
GO:0030426 IEA growth cone
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0032420 IDA stereocilium
GO:0032532 IC regulation of microvillus length
GO:0032956 IEA regulation of actin cytoskeleton organization
GO:0035556 ISA intracellular signal transduction
GO:0042989 IDA sequestering of actin monomers
GO:0044822 IEA poly(A) RNA binding
GO:0045773 IEA positive regulation of axon extension
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051016 IDA barbed-end actin filament capping
GO:0070062 IEA extracellular vesicular exosome
GO:0071300 IEA cellular response to retinoic acid
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000305533 TWF2-001 protein_coding Homo_sapiens 0 1367
ENST00000472755 TWF2-002 retained_intron Homo_sapiens 0 553
ENST00000478201 TLR9-002 nonsense_mediated_decay Homo_sapiens 2e-38 163
ENST00000494383 TLR9-001 protein_coding Homo_sapiens 0 564
ENST00000499914 TWF2-005 protein_coding Homo_sapiens 0 928

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