C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: doublesex and mab-3 related transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025755 Dmrt1-001 ENSMUSG00000024837 10090 + 19:25505618-25604329 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainLiverOvaryPlacentaTestisENSMUST00000025755
Transcript ID Bladder Brain Liver Ovary Placenta Testis
ENSMUST00000025755 0.003±0.00 0.055±0.03 0.008±0.00 0.017±0.00 0.377±0.20 4.076±1.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YF CIL_0006YF_0003 CGP 19:25236975-25604329
CIL_0008UR CIL_0008UR_0002 VISTA 19:25304027-25904976
CIL_0008NH CIL_0008NH_0002 VISTA 19:25307278-25909178
CIL_0006Y7 CIL_0006Y7_0003 CGP 19:25505618-25623920

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IMP cell morphogenesis
GO:0000987 IDA core promoter proximal region sequence-specific DNA binding
GO:0002176 IMP male germ cell proliferation
GO:0003006 IGI developmental process involved in reproduction
GO:0003682 IDA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007283 IMP spermatogenesis
GO:0008354 IMP germ cell migration
GO:0008584 IMP male gonad development
GO:0030238 IMP male sex determination
GO:0035556 IEA intracellular signal transduction
GO:0042803 IDA protein homodimerization activity
GO:0043565 IDA sequence-specific DNA binding
GO:0045835 IMP negative regulation of meiosis
GO:0045840 IMP positive regulation of mitosis
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046661 IMP male sex differentiation
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0048599 IMP oocyte development
GO:0060008 IMP Sertoli cell differentiation
GO:0060009 IMP Sertoli cell development
GO:0060903 IMP positive regulation of meiosis I
GO:1900107 IMP regulation of nodal signaling pathway
GO:2000020 IMP positive regulation of male gonad development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000382276 DMRT1-001 protein_coding Homo_sapiens 0 1066
ENST00000564322 DMRT1-003 retained_intron Homo_sapiens 0 846
ENST00000569227 DMRT1-002 protein_coding Homo_sapiens 0 728

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