C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dedicator of cytokinesis 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025831 Dock8-201 ENSMUSG00000052085 10090 + 19:24999529-25202432 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025831
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025831 3.484±1.14 5.628±1.07 14.093±3.85 0.279±0.31 8.650±3.70 4.431±0.53 0.782±0.30 7.678±1.68 2.673±1.74 13.101±0.36 0.378±0.18 8.357±1.49 5.880±4.57 1.323±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AF CIL_0009AF_0002 VISTA 19:24645396-25246544
CIL_0000VS CIL_0000VS_0002 CGP 19:24999529-25434496

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001771 IMP immunological synapse formation
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0031252 IDA cell leading edge
GO:0036336 IGI dendritic cell migration
GO:0043547 IEA positive regulation of GTPase activity
GO:0061485 IEA memory T cell proliferation
GO:0070233 IMP negative regulation of T cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000382329 DOCK8-005 protein_coding Homo_sapiens 0 5280
ENST00000382331 DOCK8-009 protein_coding Homo_sapiens 0 1657
ENST00000382341 DOCK8-002 retained_intron Homo_sapiens 0 1624
ENST00000432829 DOCK8-001 protein_coding Homo_sapiens 0 7225
ENST00000453981 DOCK8-201 protein_coding Homo_sapiens 0 7016
ENST00000454469 DOCK8-010 retained_intron Homo_sapiens 0 1834
ENST00000462618 DOCK8-016 processed_transcript Homo_sapiens 0 246
ENST00000469391 DOCK8-012 protein_coding Homo_sapiens 0 3951
ENST00000483757 DOCK8-004 nonsense_mediated_decay Homo_sapiens 0 1626
ENST00000493666 DOCK8-015 processed_transcript Homo_sapiens 0 566
ENST00000495184 DOCK8-006 retained_intron Homo_sapiens 0 5280
ENST00000524396 DOCK8-018 nonsense_mediated_decay Homo_sapiens 0 1733

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