C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dedicator of cytokinesis 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000432829 DOCK8-001 ENSG00000107099 9606 + 9:214865-465259 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000432829
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000432829 2.028±0.00 2.219±0.00 1.609±0.00 0.506±0.10 1.760±0.00 0.512±0.00 1.445±0.67 0.526±0.29 1.079±0.00 0.170±0.00 0.809±0.30 4.030±0.35 0.710±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AF CIL_0009AF_0001 VISTA 9:-140343-460780
CIL_0000VS CIL_0000VS_0001 CGP 9:214854-746106

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001771 IEA immunological synapse formation
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0016020 IDA membrane
GO:0031252 IEA cell leading edge
GO:0036336 IEA dendritic cell migration
GO:0043547 IEA positive regulation of GTPase activity
GO:0061485 IMP memory T cell proliferation
GO:0070233 IEA negative regulation of T cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025831 Dock8-201 protein_coding Mus_musculus 0 7225

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