C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA-damage inducible transcript 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026475 Ddit3-001 ENSMUSG00000025408 10090 + 10:127290774-127296288 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026475
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026475 18.013±0.51 35.112±4.10 27.062±1.84 34.667±0.00 19.043±2.50 17.640±2.02 11.079±0.29 15.682±0.91 26.246±9.29 14.748±1.82 16.685±2.66 40.729±9.17 38.401±13.31 56.003±10.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003A8 CIL_0003A8_0002 CGP 10:127281956-127296288
CIL_0003A7 CIL_0003A7_0002 CGP 10:127290774-127311786

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001955 IMP blood vessel maturation
GO:0003677 IDA DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005770 IDA late endosome
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006915 IMP apoptotic process
GO:0006983 IMP ER overload response
GO:0006986 IEA response to unfolded protein
GO:0007050 IEA cell cycle arrest
GO:0008134 IEA transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0030968 IMP endoplasmic reticulum unfolded protein response
GO:0032757 IEA positive regulation of interleukin-8 production
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0042594 IDA response to starvation
GO:0042789 IEA mRNA transcription from RNA polymerase II promoter
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044324 IDA regulation of transcription involved in anterior/posterior axis specification
GO:0045454 IEA cell redox homeostasis
GO:0045662 IMP negative regulation of myoblast differentiation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:2000016 IDA negative regulation of determination of dorsal identity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000346473 DDIT3-001 protein_coding Homo_sapiens 0 706
ENST00000537638 MARS-002 nonsense_mediated_decay Homo_sapiens 3e-33 148
ENST00000547303 DDIT3-006 protein_coding Homo_sapiens 0 754
ENST00000547526 DDIT3-004 protein_coding Homo_sapiens 0 427
ENST00000551116 DDIT3-002 protein_coding Homo_sapiens 0 593
ENST00000552740 DDIT3-005 protein_coding Homo_sapiens 0 588
ENST00000618206 DDIT3-201 protein_coding Homo_sapiens 0 699
ENST00000623876 DDIT3-003 TEC Homo_sapiens 0 438

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