C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026571 Irf7-001 ENSMUSG00000025498 10090 - 7:141263183-141266481 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000026571
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000026571 18.701±9.13 21.056±0.00 8.237±1.37 21.400±7.11 41.896±11.44 4.551±0.91 13.490±4.24 13.972±7.82 7.993±0.71 15.711±4.19 11.553±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006S8 CIL_0006S8_0003 CGP 7:141215860-141262750
CIL_0006RQ CIL_0006RQ_0003 CGP 7:141228784-141266481
CIL_0003OO CIL_0003OO_0002 CGP 7:141262706-141276786

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000982 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0002819 ISS regulation of adaptive immune response
GO:0003677 ISS DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0016064 IMP immunoglobulin mediated immune response
GO:0032607 IMP interferon-alpha production
GO:0032608 IMP interferon-beta production
GO:0032727 TAS positive regulation of interferon-alpha production
GO:0032728 TAS positive regulation of interferon-beta production
GO:0034124 IMP regulation of MyD88-dependent toll-like receptor signaling pathway
GO:0034127 IMP regulation of MyD88-independent toll-like receptor signaling pathway
GO:0045087 IEA innate immune response
GO:0045088 TAS regulation of innate immune response
GO:0045351 IMP type I interferon biosynthetic process
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0060340 IMP positive regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330243 IRF7-001 protein_coding Homo_sapiens 0 435
ENST00000348655 IRF7-005 protein_coding Homo_sapiens 0 435
ENST00000397566 IRF7-201 protein_coding Homo_sapiens 0 435
ENST00000397570 IRF7-202 protein_coding Homo_sapiens 0 435
ENST00000397574 IRF7-002 protein_coding Homo_sapiens 0 435
ENST00000469048 IRF7-004 nonsense_mediated_decay Homo_sapiens 0 435
ENST00000525445 IRF7-006 protein_coding Homo_sapiens 0 435
ENST00000531912 IRF7-013 retained_intron Homo_sapiens 0 230
ENST00000532326 IRF7-012 nonsense_mediated_decay Homo_sapiens 0 435
ENST00000533182 IRF7-007 nonsense_mediated_decay Homo_sapiens 0 435
ENST00000612534 IRF7-203 protein_coding Homo_sapiens 0 435
ENST00000617397 IRF7-204 protein_coding Homo_sapiens 0 435
ENST00000621391 IRF7-205 protein_coding Homo_sapiens 0 435

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