C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028515 Chrna1-001 ENSMUSG00000027107 10090 - 2:73563215-73580338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000028515
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000028515 0.044±0.04 0.035±0.00 0.027±0.00 0.094±0.04 0.465±0.42 0.068±0.02 0.033±0.01 0.021±0.01 0.052±0.06 0.148±0.10 2.488±0.27 0.079±0.05 0.169±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096H CIL_00096H_0002 VISTA 2:72968418-73569496
CIL_0008GI CIL_0008GI_0002 VISTA 2:72975594-73577184
CIL_0008K2 CIL_0008K2_0002 VISTA 2:72979567-73580473
CIL_0001H9 CIL_0001H9_0002 CGP 2:73429610-73580338
CIL_0001HC CIL_0001HC_0002 CGP 2:73563215-73775346

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003009 IEA skeletal muscle contraction
GO:0004889 IGI acetylcholine-activated cation-selective channel activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005892 IPI acetylcholine-gated channel complex
GO:0006812 IGI cation transport
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007528 IEA neuromuscular junction development
GO:0009986 IDA cell surface
GO:0015464 IDA acetylcholine receptor activity
GO:0019228 IEA neuronal action potential
GO:0030054 IEA cell junction
GO:0031594 IDA neuromuscular junction
GO:0042166 IGI acetylcholine binding
GO:0042391 IGI regulation of membrane potential
GO:0045211 IEA postsynaptic membrane
GO:0046716 IEA muscle cell cellular homeostasis
GO:0048630 IEA skeletal muscle tissue growth
GO:0050881 IEA musculoskeletal movement
GO:0050905 IEA neuromuscular process
GO:0070050 IEA neuron cellular homeostasis
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261007 CHRNA1-002 protein_coding Homo_sapiens 0 1467
ENST00000348749 CHRNA1-001 protein_coding Homo_sapiens 0 1722
ENST00000409219 CHRNA1-005 protein_coding Homo_sapiens 0 1269
ENST00000409323 CHRNA1-004 protein_coding Homo_sapiens 0 994
ENST00000409542 CHRNA1-003 protein_coding Homo_sapiens 0 1164
ENST00000435083 CHRNA1-006 nonsense_mediated_decay Homo_sapiens 0 1330

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