C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha 1 (muscle)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000348749 CHRNA1-001 ENSG00000138435 9606 - 2:174747592-174764472 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000348749
Transcript ID Adipose Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000348749 0.209±0.00 0.485±0.00 0.542±0.18 0.253±0.00 0.220±0.00 0.501±0.00 22.302±19.83 0.168±0.03 0.221±0.05 1.659±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001H9 CIL_0001H9_0001 CGP 2:174559572-174764472
CIL_0001HC CIL_0001HC_0001 CGP 2:174747592-175005369

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003009 IMP skeletal muscle contraction
GO:0004889 IMP acetylcholine-activated cation-selective channel activity
GO:0005216 TAS ion channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 ISS plasma membrane
GO:0005892 ISS acetylcholine-gated channel complex
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0006812 TAS cation transport
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007274 IMP neuromuscular synaptic transmission
GO:0007528 IMP neuromuscular junction development
GO:0009986 IDA cell surface
GO:0015464 ISS acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019228 IMP neuronal action potential
GO:0030054 IEA cell junction
GO:0031594 ISS neuromuscular junction
GO:0034220 TAS ion transmembrane transport
GO:0042166 ISS acetylcholine binding
GO:0042391 IMP regulation of membrane potential
GO:0045211 NAS postsynaptic membrane
GO:0046716 IMP muscle cell cellular homeostasis
GO:0048630 IMP skeletal muscle tissue growth
GO:0050881 IMP musculoskeletal movement
GO:0050905 IMP neuromuscular process
GO:0070050 IMP neuron cellular homeostasis
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028515 Chrna1-001 protein_coding Mus_musculus 0 1722

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