C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: signal peptide peptidase like 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261854 SPPL2A-001 ENSG00000138600 9606 - 15:50702266-50765808 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261854
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261854 7.345±0.00 7.095±0.00 1.281±0.00 1.388±0.83 7.090±0.00 5.906±1.80 5.753±3.24 9.254±0.00 2.079±0.78 3.668±0.00 17.446±16.55 4.002±0.72 4.497±2.00 3.037±1.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DX CIL_0002DX_0001 CGP 15:50552473-50765808
CIL_00024D CIL_00024D_0001 CGP 15:50702266-51005900

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0006508 IEA proteolysis
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0016021 IEA integral component of membrane
GO:0030660 IDA Golgi-associated vesicle membrane
GO:0031293 IDA membrane protein intracellular domain proteolysis
GO:0031902 IEA late endosome membrane
GO:0042803 IDA protein homodimerization activity
GO:0050776 IMP regulation of immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0071458 IDA integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 IDA integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028844 Sppl2a-001 protein_coding Mus_musculus 0 1467
ENSMUST00000143700 Sppl2a-003 protein_coding Mus_musculus 0 403
ENSMUST00000125592 Sppl2a-002 retained_intron Mus_musculus 0 278
ENSMUST00000179332 5730455P16Rik-201 protein_coding Mus_musculus 0.0000000004 73
ENSMUST00000103225 5730455P16Rik-001 protein_coding Mus_musculus 0.0000000004 73
ENSMUST00000024742 Nfkbie-201 protein_coding Mus_musculus 0.0000008 62

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