C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lamin A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000029699 Lmna-001 ENSMUSG00000028063 10090 - 3:88481148-88503335 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029699 27.496±5.83 16.134±1.91 43.376±2.25 2.921±0.18 24.648±11.04 89.661±13.80 9.122±2.53 9.535±1.61 8.257±2.09 27.754±2.45 5.889±1.87 25.943±8.99 17.371±4.10 0.729±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P5 CIL_0008P5_0002 VISTA 3:88218217-88823366
CIL_000898 CIL_000898_0002 VISTA 3:88224783-88827970

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005638 IDA lamin filament
GO:0005737 IEA cytoplasm
GO:0006997 IMP nucleus organization
GO:0006998 IGI nuclear envelope organization
GO:0007517 ISS muscle organ development
GO:0030010 NAS establishment of cell polarity
GO:0030334 IMP regulation of cell migration
GO:0030951 IMP establishment or maintenance of microtubule cytoskeleton polarity
GO:0034504 IMP protein localization to nucleus
GO:0035105 IMP sterol regulatory element binding protein import into nucleus
GO:0048471 ISS perinuclear region of cytoplasm
GO:0055015 IMP ventricular cardiac muscle cell development
GO:0071456 ISS cellular response to hypoxia
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria
GO:0090343 ISS positive regulation of cell aging
GO:1900180 IMP regulation of protein localization to nucleus
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000347559 LMNA-201 protein_coding Homo_sapiens 0 2263
ENST00000361308 LMNA-202 protein_coding Homo_sapiens 0 1901
ENST00000368297 LMNA-007 protein_coding Homo_sapiens 0 1683
ENST00000368298 LMNA-018 retained_intron Homo_sapiens 0 760
ENST00000368299 LMNA-004 protein_coding Homo_sapiens 0 2451
ENST00000368300 LMNA-001 protein_coding Homo_sapiens 0 2990
ENST00000368301 LMNA-002 protein_coding Homo_sapiens 0 2326
ENST00000448611 LMNA-017 protein_coding Homo_sapiens 0 2089
ENST00000459904 LMNA-015 processed_transcript Homo_sapiens 0 305
ENST00000469565 LMNA-025 processed_transcript Homo_sapiens 0 652
ENST00000470199 LMNA-023 processed_transcript Homo_sapiens 0 357
ENST00000473598 LMNA-006 protein_coding Homo_sapiens 0 2226
ENST00000478063 LMNA-024 processed_transcript Homo_sapiens 2e-24 115
ENST00000496738 LMNA-005 processed_transcript Homo_sapiens 0 710
ENST00000498722 LMNA-019 retained_intron Homo_sapiens 0 961
ENST00000502357 LMNA-026 processed_transcript Homo_sapiens 0 337
ENST00000502751 LMNA-021 processed_transcript Homo_sapiens 0 291
ENST00000504687 LMNA-028 protein_coding Homo_sapiens 0 534
ENST00000506981 LMNA-030 retained_intron Homo_sapiens 0 490
ENST00000508500 LMNA-020 protein_coding Homo_sapiens 0 612
ENST00000515459 LMNA-027 nonsense_mediated_decay Homo_sapiens 0 614
ENST00000515824 LMNA-029 retained_intron Homo_sapiens 0 394

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