C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: purinergic receptor P2X, ligand-gated ion channel 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000031429 P2rx4-001 ENSMUSG00000029470 10090 + 5:122707584-122729738 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverMuscleOvaryPlacentaTestisENSMUST00000031429
Transcript ID Brain Heart Liver Muscle Ovary Placenta Testis
ENSMUST00000031429 0.631±0.15 1.417±0.00 1.424±0.35 0.374±0.03 4.747±1.56 1.370±0.61 0.659±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZL CIL_0002ZL_0002 CGP 5:122643911-122729738
CIL_0002ZK CIL_0002ZK_0002 CGP 5:122707584-122779410

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001614 IBA purinergic nucleotide receptor activity
GO:0002028 IEA regulation of sodium ion transport
GO:0004931 IMP extracellular ATP-gated cation channel activity
GO:0005102 IEA receptor binding
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005765 IEA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006809 IDA nitric oxide biosynthetic process
GO:0006810 IEA transport
GO:0006816 IMP calcium ion transport
GO:0007165 IEA signal transduction
GO:0008144 IEA drug binding
GO:0008217 IEA regulation of blood pressure
GO:0008270 IEA zinc ion binding
GO:0010524 IEA positive regulation of calcium ion transport into cytosol
GO:0010614 IEA negative regulation of cardiac muscle hypertrophy
GO:0014069 IEA postsynaptic density
GO:0019228 IEA neuronal action potential
GO:0019233 IEA sensory perception of pain
GO:0030054 IEA cell junction
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0033198 IEA response to ATP
GO:0034220 IEA ion transmembrane transport
GO:0034405 IEA response to fluid shear stress
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0042311 IMP vasodilation
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0045177 IDA apical part of cell
GO:0045202 IEA synapse
GO:0045296 IEA cadherin binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050850 IEA positive regulation of calcium-mediated signaling
GO:0051260 IEA protein homooligomerization
GO:0051899 IEA membrane depolarization
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0055119 IEA relaxation of cardiac muscle
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0070062 IEA extracellular vesicular exosome
GO:0071318 IEA cellular response to ATP
GO:0097190 IEA apoptotic signaling pathway
GO:0098655 IMP cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000337233 P2RX4-001 protein_coding Homo_sapiens 0 1245
ENST00000359949 P2RX4-002 protein_coding Homo_sapiens 0 1053
ENST00000397924 P2RX4-007 retained_intron Homo_sapiens 0 265
ENST00000499638 P2RX4-004 retained_intron Homo_sapiens 0 717
ENST00000538417 P2RX4-014 nonsense_mediated_decay Homo_sapiens 0 425
ENST00000538701 P2RX4-011 protein_coding Homo_sapiens 0 353
ENST00000540930 P2RX4-010 processed_transcript Homo_sapiens 0 475
ENST00000541187 P2RX4-012 retained_intron Homo_sapiens 0 287
ENST00000542067 P2RX4-005 protein_coding Homo_sapiens 0 728
ENST00000543171 P2RX4-201 protein_coding Homo_sapiens 0 1070
ENST00000543318 P2RX4-006 nonsense_mediated_decay Homo_sapiens 0 789
ENST00000543430 P2RX4-008 retained_intron Homo_sapiens 0 595
ENST00000543984 P2RX4-009 nonsense_mediated_decay Homo_sapiens 0 874

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