C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000056217 ARHGEF5-001 ENSG00000050327 9606 + 7:144355340-144380632 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000056217
Transcript ID Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000056217 0.613±0.00 0.017±0.00 0.366±0.00 0.898±0.00 0.121±0.00 0.208±0.00 0.449±0.00 0.023±0.00 0.519±0.00 0.724±0.11 0.188±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074V CIL_00074V_0001 CGP 7:144318125-144380632
CIL_00074U CIL_00074U_0001 CGP 7:144355288-144410227

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002408 IEA myeloid dendritic cell chemotaxis
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005525 TAS GTP binding
GO:0030036 IEA actin cytoskeleton organization
GO:0032319 IDA regulation of Rho GTPase activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0071803 IEA positive regulation of podosome assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031750 Arhgef5-001 protein_coding Mus_musculus 0 2651
ENSMUST00000182924 Arhgef5-002 protein_coding Mus_musculus 0 1801
ENSMUST00000183094 Arhgef5-004 retained_intron Mus_musculus 0 1267
ENSMUST00000182190 Arhgef5-005 retained_intron Mus_musculus 0 1131
ENSMUST00000183313 Arhgef5-006 retained_intron Mus_musculus 0 701
ENSMUST00000183227 Arhgef5-003 retained_intron Mus_musculus 0 346
ENSMUST00000182752 Arhgef5-007 retained_intron Mus_musculus 0 344

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