C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: secretion regulating guanine nucleotide exchange factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033127 Sergef-001 ENSMUSG00000030839 10090 - 7:46443168-46639807 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000033127
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000033127 3.264±1.37 7.316±1.23 2.926±0.47 10.163±2.76 3.104±1.06 4.342±0.86 1.680±0.29 6.626±0.70 2.812±0.56 4.393±0.32 1.209±0.18 4.887±1.40 2.417±0.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000418 CIL_000418_0003 CGP 7:46396497-46639807
CIL_0001IE CIL_0001IE_0003 CGP 7:46443168-46672537

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005087 ISA Ran guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005737 ISS cytoplasm
GO:0032853 ISA positive regulation of Ran GTPase activity
GO:0045111 IEA intermediate filament cytoskeleton
GO:0050709 IEA negative regulation of protein secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265965 SERGEF-001 protein_coding Homo_sapiens 0 1201
ENST00000524589 SERGEF-020 processed_transcript Homo_sapiens 0 193
ENST00000525168 SERGEF-023 processed_transcript Homo_sapiens 9e-34 147
ENST00000525422 SERGEF-002 nonsense_mediated_decay Homo_sapiens 0 979
ENST00000525920 SERGEF-014 protein_coding Homo_sapiens 4e-34 148
ENST00000527494 SERGEF-011 nonsense_mediated_decay Homo_sapiens 0 219
ENST00000528200 SERGEF-003 protein_coding Homo_sapiens 0 219
ENST00000528369 SERGEF-017 processed_transcript Homo_sapiens 0 222
ENST00000529151 SERGEF-015 protein_coding Homo_sapiens 0 723
ENST00000529440 SERGEF-019 processed_transcript Homo_sapiens 0 219
ENST00000529728 SERGEF-004 protein_coding Homo_sapiens 0 920
ENST00000531299 SERGEF-022 processed_transcript Homo_sapiens 0 193
ENST00000531926 SERGEF-021 processed_transcript Homo_sapiens 0 193
ENST00000532546 SERGEF-018 nonsense_mediated_decay Homo_sapiens 3e-32 143
ENST00000533241 SERGEF-016 protein_coding Homo_sapiens 0 318

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