C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: secretion regulating guanine nucleotide exchange factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265965 SERGEF-001 ENSG00000129158 9606 - 11:17788048-18013162 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265965
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265965 5.600±0.00 5.605±0.00 5.489±0.00 5.173±0.00 7.567±0.00 1.782±1.42 4.434±0.00 2.090±0.60 4.836±0.00 2.720±0.00 6.449±3.06 1.805±0.36 4.771±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000418 CIL_000418_0002 CGP 11:17734812-18013162
CIL_0001IE CIL_0001IE_0002 CGP 11:17788048-18042426

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005087 TAS Ran guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0007165 TAS signal transduction
GO:0032853 TAS positive regulation of Ran GTPase activity
GO:0045111 IDA intermediate filament cytoskeleton
GO:0050709 IEA:IDA negative regulation of protein secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033127 Sergef-001 protein_coding Mus_musculus 0 1201
ENSMUST00000124962 Sergef-005 processed_transcript Mus_musculus 0 351
ENSMUST00000156147 Sergef-006 processed_transcript Mus_musculus 0 350

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