C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: secretion regulating guanine nucleotide exchange factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000528200 SERGEF-003 ENSG00000129158 9606 - 11:17788049-18013028 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000528200
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000528200 3.408±0.00 8.538±0.00 3.625±0.00 9.201±0.00 1.714±0.00 2.438±1.77 0.913±0.00 3.310±0.00 3.791±0.00 5.111±2.38 0.985±0.19 3.682±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000418 CIL_000418_0002 CGP 11:17734812-18013162
CIL_0001IE CIL_0001IE_0002 CGP 11:17788048-18042426

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005087 TAS Ran guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0007165 TAS signal transduction
GO:0032853 TAS positive regulation of Ran GTPase activity
GO:0045111 IDA intermediate filament cytoskeleton
GO:0050709 IEA:IDA negative regulation of protein secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000156147 Sergef-006 processed_transcript Mus_musculus 0 219
ENSMUST00000033127 Sergef-001 protein_coding Mus_musculus 0 219

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