C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BRCA1/BRCA2-containing complex, subunit 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033544 Brcc3-001 ENSMUSG00000031201 10090 + X:75416628-75454001 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033544
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033544 1.537±0.29 1.600±1.11 2.628±0.03 3.272±1.60 1.226±0.61 0.932±0.46 1.162±0.18 2.211±0.42 3.649±1.62 2.408±0.35 1.652±0.22 1.322±0.77 0.972±0.54 0.304±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003LJ CIL_0003LJ_0002 CGP X:75416628-75534942

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IEA ubiquitin ligase complex
GO:0000152 IEA nuclear ubiquitin ligase complex
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 ISS ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006302 ISS double-strand break repair
GO:0006508 IEA proteolysis
GO:0008237 ISS metallopeptidase activity
GO:0010165 IEA response to X-ray
GO:0010212 ISS response to ionizing radiation
GO:0030234 IEA enzyme regulator activity
GO:0031572 ISS G2 DNA damage checkpoint
GO:0031593 ISS polyubiquitin binding
GO:0045739 ISS positive regulation of DNA repair
GO:0046872 IEA metal ion binding
GO:0050790 IEA regulation of catalytic activity
GO:0070531 ISS BRCA1-A complex
GO:0070536 ISS protein K63-linked deubiquitination
GO:0070537 ISS histone H2A K63-linked deubiquitination
GO:0070552 ISS BRISC complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330045 BRCC3-002 protein_coding Homo_sapiens 0 1284
ENST00000340647 BRCC3-006 protein_coding Homo_sapiens 0 1227
ENST00000369459 BRCC3-004 protein_coding Homo_sapiens 0 774
ENST00000369462 BRCC3-001 protein_coding Homo_sapiens 0 778
ENST00000399026 BRCC3-003 protein_coding Homo_sapiens 0 307
ENST00000399042 BRCC3-201 protein_coding Homo_sapiens 0 761
ENST00000411985 BRCC3-007 protein_coding Homo_sapiens 0 523
ENST00000453705 BRCC3-005 nonsense_mediated_decay Homo_sapiens 0 1223
ENST00000508559 RP11-844P9.3-001 processed_pseudogene Homo_sapiens 0 712
ENST00000620502 BRCC3-202 protein_coding Homo_sapiens 0 1175

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