C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000217958 PSMD10-001 ENSG00000101843 9606 - X:108084207-108091618 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217958
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217958 4.943±0.00 7.194±0.00 1.207±0.00 13.280±3.51 6.516±1.41 6.982±2.86 1.873±0.55 5.265±2.47 3.864±1.88 6.882±4.38 1.822±0.06 11.710±4.89 11.647±3.35 10.590±7.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JJ CIL_0006JJ_0001 CGP X:108044970-108091618
CIL_0006JI CIL_0006JI_0001 CGP X:108084207-108154671

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005838 TAS proteasome regulatory particle
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007253 IDA cytoplasmic sequestering of NF-kappaB
GO:0008134 IPI transcription factor binding
GO:0008540 IDA proteasome regulatory particle, base subcomplex
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030307 IDA positive regulation of cell growth
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031398 IMP positive regulation of protein ubiquitination
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032436 TAS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043409 IMP negative regulation of MAPK cascade
GO:0043518 IDA negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044281 TAS small molecule metabolic process
GO:0045111 IDA intermediate filament cytoskeleton
GO:0045737 IDA positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070682 IMP proteasome regulatory particle assembly
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033805 Psmd10-001 protein_coding Mus_musculus 0 965
ENSMUST00000112978 Psmd10-002 protein_coding Mus_musculus 0 617

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