C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inhibitor of kappaB kinase beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033939 Ikbkb-001 ENSMUSG00000031537 10090 - 8:22659212-22706578 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033939
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033939 4.510±2.60 5.815±1.91 8.442±0.73 5.296±1.08 4.804±1.33 6.734±1.41 2.782±0.57 8.575±1.08 5.945±1.92 6.466±0.43 2.897±0.52 6.031±3.10 5.214±2.62 2.119±0.67

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001782 IMP B cell homeostasis
GO:0004672 IMP protein kinase activity
GO:0004702 TAS receptor signaling protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0007252 TAS I-kappaB phosphorylation
GO:0008384 IDA IkappaB kinase activity
GO:0010765 IGI positive regulation of sodium ion transport
GO:0019901 IEA protein kinase binding
GO:0023014 TAS signal transduction by phosphorylation
GO:0042501 IEA serine phosphorylation of STAT protein
GO:0042803 IEA protein homodimerization activity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0051092 ISO positive regulation of NF-kappaB transcription factor activity
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0097110 ISO scaffold protein binding
GO:2001259 IGI positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000342222 IKBKB-001 nonsense_mediated_decay Homo_sapiens 0 2113
ENST00000416505 IKBKB-201 protein_coding Homo_sapiens 0 2351
ENST00000517388 IKBKB-020 nonsense_mediated_decay Homo_sapiens 0 379
ENST00000517502 IKBKB-028 processed_transcript Homo_sapiens 0 595
ENST00000517812 IKBKB-018 nonsense_mediated_decay Homo_sapiens 0 298
ENST00000517890 IKBKB-003 nonsense_mediated_decay Homo_sapiens 0 2351
ENST00000517917 IKBKB-007 retained_intron Homo_sapiens 0 1393
ENST00000518647 IKBKB-010 retained_intron Homo_sapiens 0 1369
ENST00000518679 IKBKB-008 nonsense_mediated_decay Homo_sapiens 0 1696
ENST00000519733 IKBKB-021 nonsense_mediated_decay Homo_sapiens 0 243
ENST00000519735 IKBKB-004 protein_coding Homo_sapiens 0 907
ENST00000520201 IKBKB-009 retained_intron Homo_sapiens 0 1631
ENST00000520320 IKBKB-017 nonsense_mediated_decay Homo_sapiens 0 243
ENST00000520655 IKBKB-012 nonsense_mediated_decay Homo_sapiens 0 1879
ENST00000520810 IKBKB-002 protein_coding Homo_sapiens 0 2601
ENST00000520835 IKBKB-006 protein_coding Homo_sapiens 0 2451
ENST00000521661 IKBKB-011 nonsense_mediated_decay Homo_sapiens 0 1881
ENST00000523105 IKBKB-005 nonsense_mediated_decay Homo_sapiens 0 1631
ENST00000523517 IKBKB-013 nonsense_mediated_decay Homo_sapiens 0 1363

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