C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: platelet derived growth factor, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000046901 Pdgfa-002 ENSMUSG00000025856 10090 - 5:138976516-138994953 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046901
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046901 6.297±3.10 14.871±4.88 5.392±0.00 5.462±1.34 35.030±1.58 3.193±0.14 4.093±0.54 0.678±0.41 28.551±2.67 4.805±0.30 9.541±3.61 8.578±9.56 1.954±0.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018I CIL_00018I_0002 CGP 5:138976014-139150001

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IDA angiogenesis
GO:0001942 IMP hair follicle development
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0005161 IBA platelet-derived growth factor receptor binding
GO:0005902 IDA microvillus
GO:0007596 IBA blood coagulation
GO:0008083 IEA growth factor activity
GO:0008284 IMP positive regulation of cell proliferation
GO:0009887 IMP organ morphogenesis
GO:0014068 IBA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030031 IDA cell projection assembly
GO:0030036 IDA actin cytoskeleton organization
GO:0030335 IBA positive regulation of cell migration
GO:0031954 IBA positive regulation of protein autophosphorylation
GO:0043406 IBA positive regulation of MAP kinase activity
GO:0043588 IMP skin development
GO:0048008 IBA platelet-derived growth factor receptor signaling pathway
GO:0048286 IMP lung alveolus development
GO:0050730 IDA regulation of peptidyl-tyrosine phosphorylation
GO:0051781 IEA positive regulation of cell division
GO:0060683 IMP regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
GO:0070374 IBA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000354513 PDGFA-002 protein_coding Homo_sapiens 0 1223
ENST00000400761 PDGFA-005 protein_coding Homo_sapiens 0 579
ENST00000402802 PDGFA-001 protein_coding Homo_sapiens 0 928
ENST00000405692 PDGFA-006 protein_coding Homo_sapiens 0 435
ENST00000426681 PDGFA-004 processed_transcript Homo_sapiens 1e-37 159
ENST00000482462 PDGFA-003 retained_intron Homo_sapiens 0 438

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