C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cereblon
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000049675 Crbn-003 ENSMUSG00000005362 10090 - 6:106778249-106800069 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000049675
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000049675 2.736±0.97 5.029±1.22 5.697±0.19 5.493±0.64 3.615±0.84 2.367±0.71 2.996±1.04 5.010±0.52 3.896±0.98 3.937±0.65 3.809±1.14 3.882±1.65 3.674±1.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050N CIL_00050N_0002 CGP 6:106711975-106782474
CIL_00050M CIL_00050M_0002 CGP 6:106769120-106800074

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004176 IEA ATP-dependent peptidase activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005737 ISS cytoplasm
GO:0006200 IEA ATP catabolic process
GO:0016020 IEA membrane
GO:0016567 ISS protein ubiquitination
GO:0031464 ISS Cul4A-RING E3 ubiquitin ligase complex
GO:0032463 IEA negative regulation of protein homooligomerization
GO:0034766 IEA negative regulation of ion transmembrane transport
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0090073 IEA positive regulation of protein homodimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000231948 CRBN-001 protein_coding Homo_sapiens 0 1720
ENST00000251607 TRNT1-001 protein_coding Homo_sapiens 0 339
ENST00000280591 TRNT1-004 protein_coding Homo_sapiens 0 337
ENST00000424814 CRBN-005 protein_coding Homo_sapiens 0 1251
ENST00000432408 CRBN-004 protein_coding Homo_sapiens 0 1707
ENST00000434583 TRNT1-010 nonsense_mediated_decay Homo_sapiens 0 339
ENST00000438230 RP1-37M3.8-001 processed_pseudogene Homo_sapiens 0 291
ENST00000450014 CRBN-010 protein_coding Homo_sapiens 0 765
ENST00000450164 RP11-267N12.2-001 processed_pseudogene Homo_sapiens 0 226
ENST00000459840 CRBN-009 retained_intron Homo_sapiens 0 815
ENST00000478353 CRBN-011 retained_intron Homo_sapiens 0 429
ENST00000480249 CRBN-008 retained_intron Homo_sapiens 0 556
ENST00000482844 CRBN-007 retained_intron Homo_sapiens 0 599
ENST00000488263 CRBN-006 retained_intron Homo_sapiens 0 527
ENST00000491834 CRBN-003 retained_intron Homo_sapiens 0 667
ENST00000498442 CRBN-013 retained_intron Homo_sapiens 0 529
ENST00000498700 CRBN-012 retained_intron Homo_sapiens 0 610

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