C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cereblon
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000231948 CRBN-001 ENSG00000113851 9606 - 3:3150011-3179710 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000231948
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000231948 5.978±0.00 10.343±0.00 3.381±0.00 11.143±2.03 7.445±0.95 7.792±3.74 4.806±2.76 4.073±0.34 4.289±1.63 7.437±0.00 5.274±2.41 5.513±1.00 16.752±1.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050N CIL_00050N_0001 CGP 3:3066326-3150879
CIL_00050M CIL_00050M_0001 CGP 3:3126916-3179710

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004176 IEA ATP-dependent peptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006200 IEA ATP catabolic process
GO:0006508 IEA proteolysis
GO:0016020 IEA membrane
GO:0016567 IEA protein ubiquitination
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0032463 IEA negative regulation of protein homooligomerization
GO:0034766 IEA negative regulation of ion transmembrane transport
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0090073 IEA positive regulation of protein homodimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113239 Crbn-001 protein_coding Mus_musculus 0 1729
ENSMUST00000049675 Crbn-003 protein_coding Mus_musculus 0 1720
ENSMUST00000013882 Crbn-002 protein_coding Mus_musculus 0 1711
ENSMUST00000151484 Crbn-005 processed_transcript Mus_musculus 0 841
ENSMUST00000147087 Crbn-004 retained_intron Mus_musculus 0 791

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