C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box C2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000054691 Foxc2-001 ENSMUSG00000046714 10090 + 8:121116171-121118895 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L5 CIL_0008L5_0002 VISTA 8:120702895-121303512
CIL_0008XN CIL_0008XN_0002 VISTA 8:120870103-121471139
CIL_00099Z CIL_00099Z_0002 VISTA 8:120975683-121578530
CIL_0008WM CIL_0008WM_0002 VISTA 8:120983047-121584421
CIL_0008VY CIL_0008VY_0002 VISTA 8:121000361-121603557
CIL_00023B CIL_00023B_0002 CGP 8:121095012-121118895
CIL_0002T4 CIL_0002T4_0002 CGP 8:121116171-121130644

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001501 IGI skeletal system development
GO:0001503 IMP ossification
GO:0001568 IGI blood vessel development
GO:0001569 IGI patterning of blood vessels
GO:0001656 IMP metanephros development
GO:0001657 IMP ureteric bud development
GO:0001756 IGI somitogenesis
GO:0001822 IMP kidney development
GO:0001945 IGI lymph vessel development
GO:0001946 ISS lymphangiogenesis
GO:0001974 IGI blood vessel remodeling
GO:0003007 IGI heart morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IGI RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005634 IC nucleus
GO:0006366 IGI transcription from RNA polymerase II promoter
GO:0007219 IGI Notch signaling pathway
GO:0007507 IMP heart development
GO:0008283 IMP cell proliferation
GO:0008286 ISS insulin receptor signaling pathway
GO:0009725 ISS response to hormone
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0014032 IGI neural crest cell development
GO:0030199 IMP collagen fibril organization
GO:0031490 ISS chromatin DNA binding
GO:0033625 IC positive regulation of integrin activation
GO:0033630 IDA positive regulation of cell adhesion mediated by integrin
GO:0035050 IGI embryonic heart tube development
GO:0035470 IDA positive regulation of vascular wound healing
GO:0043010 IMP camera-type eye development
GO:0043565 ISS sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046620 IGI regulation of organ growth
GO:0048010 IGI vascular endothelial growth factor receptor signaling pathway
GO:0048341 IGI paraxial mesoderm formation
GO:0048343 IMP paraxial mesodermal cell fate commitment
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048703 IMP embryonic viscerocranium morphogenesis
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0048844 IMP artery morphogenesis
GO:0050880 IGI regulation of blood vessel size
GO:0055010 IGI ventricular cardiac muscle tissue morphogenesis
GO:0060038 IGI cardiac muscle cell proliferation
GO:0072011 IMP glomerular endothelium development
GO:0072112 IMP glomerular visceral epithelial cell differentiation
GO:0072144 IMP glomerular mesangial cell development
GO:0090050 IDA positive regulation of cell migration involved in sprouting angiogenesis
GO:1902257 IGI negative regulation of apoptotic process involved in outflow tract morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000122732 foxc1a-001 protein_coding Danio_rerio 0 250
ENST00000313071 FOXG1-001 protein_coding Homo_sapiens 0 202
ENST00000320241 FOXL1-001 protein_coding Homo_sapiens 0 279
ENST00000320354 FOXC2-001 protein_coding Homo_sapiens 0 1781
ENST00000375978 FOXS1-001 protein_coding Homo_sapiens 0 219
ENST00000380874 FOXC1-001 protein_coding Homo_sapiens 0 529
ENST00000593625 FOXL1-002 protein_coding Homo_sapiens 0 233

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