C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box C1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380874 FOXC1-001 ENSG00000054598 9606 + 6:1609972-1613897 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380874
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380874 8.329±0.00 6.627±0.00 2.373±0.00 1.513±0.88 2.671±1.93 1.269±1.00 1.448±0.93 9.096±9.02 0.831±0.68 4.488±3.37 1.204±1.06 3.881±1.36 4.932±1.72 5.778±3.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038B CIL_00038B_0001 CGP 6:1389834-1613897
CIL_0005SP CIL_0005SP_0002 CGP 6:1609972-2245692

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IC RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001501 IEA skeletal system development
GO:0001503 IEA ossification
GO:0001541 IEA ovarian follicle development
GO:0001568 IEA blood vessel development
GO:0001654 IDA eye development
GO:0001657 IEA ureteric bud development
GO:0001701 IEA in utero embryonic development
GO:0001756 IEA somitogenesis
GO:0001822 IEA kidney development
GO:0001945 IEA lymph vessel development
GO:0001974 IEA blood vessel remodeling
GO:0003007 IEA heart morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005720 IDA nuclear heterochromatin
GO:0005737 IDA cytoplasm
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007219 IEA Notch signaling pathway
GO:0007420 IEA brain development
GO:0007507 IDA heart development
GO:0008134 IPI transcription factor binding
GO:0008301 IDA DNA binding, bending
GO:0008354 IEA germ cell migration
GO:0014032 IEA neural crest cell development
GO:0030199 IEA collagen fibril organization
GO:0030203 IEA glycosaminoglycan metabolic process
GO:0032808 IEA lacrimal gland development
GO:0035050 IEA embryonic heart tube development
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0043010 IEA camera-type eye development
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046620 IEA regulation of organ growth
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway
GO:0048341 IEA paraxial mesoderm formation
GO:0048762 IEA mesenchymal cell differentiation
GO:0048844 IEA artery morphogenesis
GO:0050880 IEA regulation of blood vessel size
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis
GO:0060038 IEA cardiac muscle cell proliferation
GO:1902257 IEA negative regulation of apoptotic process involved in outflow tract morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062292 Foxc1-001 protein_coding Mus_musculus 0 3666
ENSMUST00000054691 Foxc2-001 protein_coding Mus_musculus 0 529
ENSDART00000122732 foxc1a-001 protein_coding Danio_rerio 0 444
ENSDART00000077753 foxc1b-001 protein_coding Danio_rerio 0 405
ENSMUST00000181609 Foxl1-001 protein_coding Mus_musculus 0 254
ENSMUST00000087285 Foxd3-001 protein_coding Mus_musculus 0 250
ENSMUST00000105098 Foxd1-001 protein_coding Mus_musculus 0 220
ENSMUST00000072915 Foxb2-201 protein_coding Mus_musculus 8.96831e-44 183
ENSMUST00000058600 Foxd4-201 protein_coding Mus_musculus 4.99997e-41 174
ENSMUST00000042054 Foxf2-001 protein_coding Mus_musculus 4e-22 111

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