C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: gremlin 2, DAN family BMP antagonist
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000318160 GREM2-001 ENSG00000180875 9606 - 1:240489573-240612149 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318160
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318160 0.063±0.00 0.715±0.00 0.105±0.00 1.599±0.82 1.388±0.78 4.426±3.06 0.009±0.00 2.015±1.72 2.403±1.76 0.613±0.22 0.082±0.00 0.859±0.48 0.930±0.36 1.162±0.99

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KG CIL_0006KG_0001 CGP 1:240014348-240612149
CIL_0000L0 CIL_0000L0_0002 CGP 1:240489573-241357230

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0008201 ISS heparin binding
GO:0010172 ISS embryonic body morphogenesis
GO:0019221 ISS cytokine-mediated signaling pathway
GO:0030509 TAS BMP signaling pathway
GO:0030514 IEA negative regulation of BMP signaling pathway
GO:0036122 IEA BMP binding
GO:0038098 IEA sequestering of BMP from receptor via BMP binding
GO:0042803 IEA protein homodimerization activity
GO:0048263 IEA determination of dorsal identity
GO:0060300 ISS regulation of cytokine activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000055294 Grem2-001 protein_coding Mus_musculus 0 883
ENSDART00000103870 GREM1 (2 of 3)-001 protein_coding Danio_rerio 0 198

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