C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: vav 2 oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000056176 Vav2-001 ENSMUSG00000009621 10090 - 2:27262104-27427033 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056176
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056176 4.588±1.31 15.620±4.03 6.886±0.91 12.688±0.00 7.943±4.13 4.383±1.56 4.433±0.42 8.478±3.70 3.875±2.03 11.759±4.04 0.479±0.11 8.669±4.63 8.760±6.19 6.375±4.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014Y CIL_00014Y_0002 CGP 2:27188393-27427033
CIL_00014Z CIL_00014Z_0002 CGP 2:27262104-27507662

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005085 IMP guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005154 IPI epidermal growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007264 IMP small GTPase mediated signal transduction
GO:0010468 IEA regulation of gene expression
GO:0016477 IGI cell migration
GO:0030031 IGI cell projection assembly
GO:0030032 IGI lamellipodium assembly
GO:0030193 IEA regulation of blood coagulation
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IMP positive regulation of GTPase activity
GO:0043552 IGI positive regulation of phosphatidylinositol 3-kinase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000371850 VAV2-001 protein_coding Homo_sapiens 0 3057
ENST00000371851 VAV2-002 protein_coding Homo_sapiens 0 3314
ENST00000406606 VAV2-003 protein_coding Homo_sapiens 0 2822
ENST00000486113 VAV2-004 processed_transcript Homo_sapiens 0 492

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