C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inhibitor of kappaB kinase beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000063401 Ikbkb-011 ENSMUSG00000031537 10090 - 8:22659768-22706589 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryTestisENSMUST00000063401
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Testis
ENSMUST00000063401 2.054±0.53 1.748±0.64 3.413±1.30 3.392±0.89 2.180±0.34 1.028±0.04 1.881±0.29 1.538±0.32 2.915±0.40 2.173±0.66 0.988±0.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001782 IMP B cell homeostasis
GO:0004672 ISS protein kinase activity
GO:0004702 TAS receptor signaling protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 TAS cytoplasm
GO:0007252 TAS I-kappaB phosphorylation
GO:0008384 IDA IkappaB kinase activity
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0010765 IGI positive regulation of sodium ion transport
GO:0023014 TAS signal transduction by phosphorylation
GO:0035631 IDA CD40 receptor complex
GO:0042803 ISS protein homodimerization activity
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046982 ISS protein heterodimerization activity
GO:0051092 ISO positive regulation of NF-kappaB transcription factor activity
GO:0071356 ISS cellular response to tumor necrosis factor
GO:0097110 ISO scaffold protein binding
GO:2001259 IGI positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000342222 IKBKB-001 nonsense_mediated_decay Homo_sapiens 0 2069
ENST00000416505 IKBKB-201 protein_coding Homo_sapiens 0 2307
ENST00000517388 IKBKB-020 nonsense_mediated_decay Homo_sapiens 0 379
ENST00000517502 IKBKB-028 processed_transcript Homo_sapiens 0 595
ENST00000517812 IKBKB-018 nonsense_mediated_decay Homo_sapiens 0 298
ENST00000517890 IKBKB-003 nonsense_mediated_decay Homo_sapiens 0 2307
ENST00000517917 IKBKB-007 retained_intron Homo_sapiens 0 1393
ENST00000518647 IKBKB-010 retained_intron Homo_sapiens 0 1369
ENST00000518679 IKBKB-008 nonsense_mediated_decay Homo_sapiens 0 1652
ENST00000519733 IKBKB-021 nonsense_mediated_decay Homo_sapiens 0 243
ENST00000519735 IKBKB-004 protein_coding Homo_sapiens 0 907
ENST00000520201 IKBKB-009 retained_intron Homo_sapiens 0 1631
ENST00000520320 IKBKB-017 nonsense_mediated_decay Homo_sapiens 0 243
ENST00000520655 IKBKB-012 nonsense_mediated_decay Homo_sapiens 0 1879
ENST00000520810 IKBKB-002 protein_coding Homo_sapiens 0 2556
ENST00000520835 IKBKB-006 protein_coding Homo_sapiens 0 2407
ENST00000521661 IKBKB-011 nonsense_mediated_decay Homo_sapiens 0 1881
ENST00000523105 IKBKB-005 nonsense_mediated_decay Homo_sapiens 0 1631
ENST00000523517 IKBKB-013 nonsense_mediated_decay Homo_sapiens 0 1363

Loading