C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SMAD family member 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000545620 SMAD5-201 ENSG00000113658 9606 + 5:136132847-136182734 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000545620
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000545620 5.701±0.00 4.945±0.00 2.472±0.12 3.798±1.03 3.626±2.61 2.018±1.23 6.490±0.00 5.256±2.99 4.783±0.00 1.584±0.92 3.753±2.44 3.573±0.94 4.449±2.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005P2 CIL_0005P2_0001 CGP 5:136028895-136188747
CIL_0005P3 CIL_0005P3_0001 CGP 5:136132845-136365537

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005057 NAS receptor signaling protein activity
GO:0005515 IPI:IEA protein binding
GO:0005622 NAS:IEA intracellular
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 NAS signal transduction
GO:0007179 NAS:IEA transforming growth factor beta receptor signaling pathway
GO:0009880 ISS embryonic pattern specification
GO:0016021 NAS integral component of membrane
GO:0030509 ISS BMP signaling pathway
GO:0030618 TAS transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035556 TAS intracellular signal transduction
GO:0043234 IDA protein complex
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0071773 ISS cellular response to BMP stimulus
GO:1901522 ISS positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000069557 Smad5-001 protein_coding Mus_musculus 0 2409
ENSMUST00000109874 Smad5-003 protein_coding Mus_musculus 0 2307
ENSMUST00000109876 Smad5-002 protein_coding Mus_musculus 0 2307
ENSMUST00000138677 Smad5-004 processed_transcript Mus_musculus 0 1600
ENSMUST00000132302 Smad5-005 processed_transcript Mus_musculus 0 1227
ENSMUST00000066091 Smad1-001 protein_coding Mus_musculus 0 809
ENSMUST00000109885 Smad1-002 protein_coding Mus_musculus 0 673
ENSMUST00000136702 Smad5-006 processed_transcript Mus_musculus 0 427

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