C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: collagen triple helix repeat containing 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000067072 Cthrc1-001 ENSMUSG00000054196 10090 + 15:39076932-39087119 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067072
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067072 1.055±0.26 3.431±1.05 1.680±0.26 6.264±4.24 2.270±0.28 0.494±0.15 0.241±0.08 0.226±0.09 0.809±0.67 2.403±0.41 0.160±0.09 1.605±0.85 5.165±2.42 0.264±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060D CIL_00060D_0002 CGP 15:39006280-39087121
CIL_0004T6 CIL_0004T6_0003 CGP 15:39076932-39112716

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005109 IPI frizzled binding
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005581 IEA collagen trimer
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0016477 IEA cell migration
GO:0017147 IPI Wnt-protein binding
GO:0031012 IEA extracellular matrix
GO:0032092 IDA positive regulation of protein binding
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0043932 IMP ossification involved in bone remodeling
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0060071 IMP Wnt signaling pathway, planar cell polarity pathway
GO:0060122 IGI inner ear receptor stereocilium organization
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:0090103 IGI cochlea morphogenesis
GO:0090177 IGI establishment of planar polarity involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330295 CTHRC1-001 protein_coding Homo_sapiens 0 948
ENST00000415886 CTHRC1-004 protein_coding Homo_sapiens 0 420
ENST00000520337 CTHRC1-003 protein_coding Homo_sapiens 0 815
ENST00000520880 CTHRC1-002 protein_coding Homo_sapiens 0 448

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