C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor coactivator 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000068304 Ncoa2-201 ENSMUSG00000005886 10090 - 1:13139159-13374083 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068304
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068304 2.588±1.21 3.486±1.08 2.045±0.00 3.786±1.91 2.681±1.09 3.615±1.84 2.441±1.09 3.617±1.68 2.310±1.61 5.799±0.18 1.183±0.23 3.798±1.89 4.107±1.64 3.738±0.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ME CIL_0007ME_0002 UCNEbase 1:13097855-13197231
CIL_0003BO CIL_0003BO_0002 CGP 1:13113457-13374083
CIL_0003BN CIL_0003BN_0002 CGP 1:13139105-13589910

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003713 IDA transcription coactivator activity
GO:0004402 IEA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0016573 IEA histone acetylation
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IDA thyroid hormone receptor coactivator activity
GO:0035257 IEA nuclear hormone receptor binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:2000273 IDA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000452400 NCOA2-001 protein_coding Homo_sapiens 0 3627
ENST00000518287 NCOA2-002 nonsense_mediated_decay Homo_sapiens 0 5308
ENST00000518363 NCOA2-005 protein_coding Homo_sapiens 0 2183
ENST00000519724 NCOA2-004 protein_coding Homo_sapiens 3e-25 119
ENST00000520416 NCOA2-003 protein_coding Homo_sapiens 1e-24 117
ENST00000521239 NCOA2-007 retained_intron Homo_sapiens 0 405
ENST00000524223 NCOA2-008 processed_transcript Homo_sapiens 0 905

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