C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transducin-like enhancer of split 1, homolog of Drosophila E(spl)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000072695 Tle1-001 ENSMUSG00000008305 10090 - 4:72117805-72200857 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072695
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072695 8.324±3.62 8.994±4.39 5.258±0.62 9.497±3.12 5.576±1.64 6.101±2.15 0.879±0.30 2.224±0.80 4.378±1.97 4.911±1.73 1.659±0.70 11.382±4.09 2.082±0.78 1.842±0.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KE CIL_0007KE_0004 UCNEbase 4:70810873-73489292
CIL_00090V CIL_00090V_0002 VISTA 4:71539683-72141070
CIL_0008X3 CIL_0008X3_0002 VISTA 4:71768926-72369840
CIL_0009AO CIL_0009AO_0002 VISTA 4:71866327-72468960
CIL_0008C4 CIL_0008C4_0002 VISTA 4:71896487-72497365
CIL_0008TV CIL_0008TV_0002 VISTA 4:72081989-72683115

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IEA RNA polymerase II transcription corepressor activity
GO:0003682 IDA chromatin binding
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0008134 IEA transcription factor binding
GO:0010628 IEA positive regulation of gene expression
GO:0042802 IEA identical protein binding
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:2000811 IEA negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262953 TLE2-004 protein_coding Homo_sapiens 0 641
ENST00000265284 TLE4-018 protein_coding Homo_sapiens 0 1290
ENST00000376463 TLE1-005 protein_coding Homo_sapiens 0 784
ENST00000376472 TLE1-201 protein_coding Homo_sapiens 0 3031
ENST00000376499 TLE1-001 protein_coding Homo_sapiens 0 3140
ENST00000376537 TLE4-015 protein_coding Homo_sapiens 0 1290
ENST00000376544 TLE4-201 protein_coding Homo_sapiens 0 1290
ENST00000376552 TLE4-008 protein_coding Homo_sapiens 0 1290
ENST00000418319 TLE1-002 protein_coding Homo_sapiens 0 689
ENST00000422965 TLE1P1-001 processed_pseudogene Homo_sapiens 0 872
ENST00000426948 TLE2-201 protein_coding Homo_sapiens 0 525
ENST00000443826 TLE2-002 protein_coding Homo_sapiens 0 641
ENST00000455444 TLE2-202 protein_coding Homo_sapiens 0 641
ENST00000462803 TLE4-016 nonsense_mediated_decay Homo_sapiens 0 1290
ENST00000464999 TLE1-003 processed_transcript Homo_sapiens 0 281
ENST00000470872 TLE4-014 nonsense_mediated_decay Homo_sapiens 0 1290
ENST00000478290 TLE4-005 processed_transcript Homo_sapiens 0 451
ENST00000491534 TLE1-006 processed_transcript Homo_sapiens 0 496
ENST00000496114 TLE4-030 protein_coding Homo_sapiens 0 289
ENST00000590536 TLE2-006 protein_coding Homo_sapiens 0 638
ENST00000591529 TLE2-001 protein_coding Homo_sapiens 0 525

Loading