C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000074618 Nfatc2-002 ENSMUSG00000027544 10090 - 2:168476410-168590260 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaENSMUST00000074618
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000074618 0.399±0.00 0.619±0.00 0.147±0.07 1.192±0.29 0.322±0.04 0.379±0.19 0.034±0.01 0.189±0.00 0.631±0.18 0.374±0.20 0.157±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000153 CIL_000153_0002 CGP 2:168260117-168601657
CIL_0007HZ CIL_0007HZ_0002 CGP 2:168476410-168742409

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001816 IDA cytokine production
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IPI transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0010628 IMP positive regulation of gene expression
GO:0015629 IEA actin cytoskeleton
GO:0016477 ISS cell migration
GO:0030529 IDA ribonucleoprotein complex
GO:0030890 IEA positive regulation of B cell proliferation
GO:0042493 IEA response to drug
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045893 ISO positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050853 IEA B cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000371564 NFATC2-001 protein_coding Homo_sapiens 0 3029
ENST00000396009 NFATC2-002 protein_coding Homo_sapiens 0 3101
ENST00000414705 NFATC2-004 protein_coding Homo_sapiens 0 2894
ENST00000609507 NFATC2-006 protein_coding Homo_sapiens 0 2215
ENST00000609943 NFATC2-005 protein_coding Homo_sapiens 0 2966
ENST00000610033 NFATC2-007 protein_coding Homo_sapiens 0 2215

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