C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396009 NFATC2-002 ENSG00000101096 9606 - 20:51386957-51542719 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonKidneyLungOvaryPlacentaTestisENST00000396009
Transcript ID Brain Breast Colon Kidney Lung Ovary Placenta Testis
ENST00000396009 0.473±0.00 0.508±0.00 0.245±0.00 0.658±0.00 1.003±0.51 0.569±0.19 0.732±0.00 0.211±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000153 CIL_000153_0001 CGP 20:51003656-51562831
CIL_0007HZ CIL_0007HZ_0001 CGP 20:51386957-51768634

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001816 IEA cytokine production
GO:0003677 TAS DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS:IEA regulation of transcription, DNA-templated
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0010628 IEA positive regulation of gene expression
GO:0015629 IDA actin cytoskeleton
GO:0016477 IDA cell migration
GO:0030529 IEA ribonucleoprotein complex
GO:0030890 IMP positive regulation of B cell proliferation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042493 IMP response to drug
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044798 IEA nuclear transcription factor complex
GO:0045087 TAS innate immune response
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050853 IMP B cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000074618 Nfatc2-002 protein_coding Mus_musculus 0 3101
ENSMUST00000109184 Nfatc2-001 protein_coding Mus_musculus 0 3029
ENSMUST00000029057 Nfatc2-005 protein_coding Mus_musculus 0 2185
ENSMUST00000137451 Nfatc2-004 protein_coding Mus_musculus 0 2054
ENSMUST00000140137 Nfatc2-007 retained_intron Mus_musculus 0 2036
ENSMUST00000138546 Nfatc2-008 retained_intron Mus_musculus 0 1613
ENSMUST00000151292 Nfatc2-003 processed_transcript Mus_musculus 0 1417
ENSMUST00000171689 Nfatc2-201 protein_coding Mus_musculus 0 1376
ENSMUST00000099067 Nfatc2-006 processed_transcript Mus_musculus 0 1376
ENSDART00000112656 NFATC2 (1 of 2)-201 protein_coding Danio_rerio 0 409

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