C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF7)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000074856 Arhgef7-001 ENSMUSG00000031511 10090 + 8:11758354-11835219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074856
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074856 11.149±4.17 14.459±1.44 10.312±1.22 11.864±2.40 11.098±4.99 11.934±3.17 17.232±2.25 17.415±3.26 4.144±1.33 19.323±6.93 7.624±2.79 17.272±4.99 12.443±5.25 5.380±1.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00080T CIL_00080T_0002 VISTA 8:11596202-12196925
CIL_0007MP CIL_0007MP_0002 UCNEbase 8:11623645-11913000
CIL_00012L CIL_00012L_0002 CGP 8:11728105-11855761

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002244 IGI hematopoietic progenitor cell differentiation
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0007399 IEA nervous system development
GO:0019901 IPI protein kinase binding
GO:0030027 IDA lamellipodium
GO:0030032 IMP lamellipodium assembly
GO:0030054 IEA cell junction
GO:0032855 IMP positive regulation of Rac GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043065 ISS positive regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000218789 ARHGEF7-001 protein_coding Homo_sapiens 0 2121
ENST00000317133 ARHGEF7-008 protein_coding Homo_sapiens 0 2104
ENST00000375723 ARHGEF7-005 protein_coding Homo_sapiens 0 1982
ENST00000375736 ARHGEF7-007 protein_coding Homo_sapiens 0 2451
ENST00000375739 ARHGEF7-201 protein_coding Homo_sapiens 0 1982
ENST00000375741 ARHGEF7-202 protein_coding Homo_sapiens 0 1982
ENST00000426073 ARHGEF7-004 protein_coding Homo_sapiens 0 2314
ENST00000426768 ARHGEF7-009 protein_coding Homo_sapiens 0 459
ENST00000449979 ARHGEF7-003 protein_coding Homo_sapiens 0 455
ENST00000466143 ARHGEF7-013 protein_coding Homo_sapiens 0 1749
ENST00000467053 ARHGEF7-016 protein_coding Homo_sapiens 0 453
ENST00000469877 ARHGEF7-012 nonsense_mediated_decay Homo_sapiens 0 335
ENST00000478679 ARHGEF7-011 protein_coding Homo_sapiens 0 1428
ENST00000483540 ARHGEF7-014 processed_transcript Homo_sapiens 4e-19 99
ENST00000491688 ARHGEF7-006 processed_transcript Homo_sapiens 0 387
ENST00000491775 ARHGEF7-015 protein_coding Homo_sapiens 0 248
ENST00000544132 ARHGEF7-018 protein_coding Homo_sapiens 0 348

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