C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin-1 receptor-associated kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000074936 Irak4-001 ENSMUSG00000059883 10090 + 15:94543643-94568306 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074936
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074936 4.722±0.29 4.751±1.14 6.970±0.64 4.842±0.63 8.280±1.75 1.325±0.17 4.758±0.31 3.124±0.66 4.538±0.77 0.480±0.08 5.609±0.68 9.169±1.34 2.115±0.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006R6 CIL_0006R6_0002 CGP 15:94522688-94581815
CIL_0006R5 CIL_0006R5_0002 CGP 15:94543643-94589889

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001816 IDA cytokine production
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005149 IPI interleukin-1 receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0007254 IEA JNK cascade
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 IEA innate immune response
GO:0048661 IEA positive regulation of smooth muscle cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000431837 IRAK4-201 protein_coding Homo_sapiens 0 756
ENST00000440781 IRAK4-005 protein_coding Homo_sapiens 0 756
ENST00000448290 IRAK4-001 protein_coding Homo_sapiens 0 1003
ENST00000547101 IRAK4-004 nonsense_mediated_decay Homo_sapiens 0 852
ENST00000547521 IRAK4-007 nonsense_mediated_decay Homo_sapiens 0 612
ENST00000547928 IRAK4-012 retained_intron Homo_sapiens 0 438
ENST00000550386 IRAK4-003 nonsense_mediated_decay Homo_sapiens 0 852
ENST00000550615 IRAK4-006 nonsense_mediated_decay Homo_sapiens 0 756
ENST00000551736 IRAK4-002 protein_coding Homo_sapiens 0 1002
ENST00000552309 IRAK4-010 nonsense_mediated_decay Homo_sapiens 0 451
ENST00000613694 IRAK4-202 protein_coding Homo_sapiens 0 1002

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