C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase, Mg2+/Mn2+ dependent, 1B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378551 PPM1B-002 ENSG00000138032 9606 + 2:44168877-44234646 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378551
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378551 4.948±0.00 4.063±0.00 0.916±0.00 3.286±0.00 5.733±1.99 4.293±1.29 1.243±0.48 6.359±2.57 4.430±2.17 1.949±0.09 4.036±2.58 4.395±1.56 2.377±0.20 4.101±1.77

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XM CIL_0001XM_0001 CGP 2:43886508-44244384
CIL_0004BC CIL_0004BC_0001 CGP 2:44167969-44321494

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0003824 IEA catalytic activity
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 IEA:IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005829 ISS cytosol
GO:0006470 IEA:IMP protein dephosphorylation
GO:0006499 ISS N-terminal protein myristoylation
GO:0016020 ISS membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030145 IEA manganese ion binding
GO:0032688 IMP negative regulation of interferon-beta production
GO:0035970 IDA peptidyl-threonine dephosphorylation
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050687 IMP negative regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112304 Ppm1b-202 protein_coding Mus_musculus 0 3343
ENSMUST00000080217 Ppm1b-201 protein_coding Mus_musculus 0 1796
ENSMUST00000112307 Ppm1b-204 protein_coding Mus_musculus 0 1491
ENSMUST00000112305 Ppm1b-203 protein_coding Mus_musculus 0 1487
ENSMUST00000187459 RP23-193H10.1-001 processed_pseudogene Mus_musculus 0 1483

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