C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha polypeptide 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000093844 Chrna5-201 ENSMUSG00000035594 10090 + 9:54980880-55007779 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000093844
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000093844 0.044±0.04 0.102±0.04 0.019±0.01 0.332±0.02 0.126±0.04 0.081±0.02 0.027±0.01 0.033±0.00 0.011±0.01 0.016±0.00 0.012±0.00 0.111±0.06 2.129±0.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TW CIL_0003TW_0002 CGP 9:54950790-55007779
CIL_0003TT CIL_0003TT_0002 CGP 9:54980880-55026559

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005892 IPI acetylcholine-gated channel complex
GO:0015464 IEA acetylcholine receptor activity
GO:0030054 IEA cell junction
GO:0035094 IMP response to nicotine
GO:0035095 IEA behavioral response to nicotine
GO:0045211 IEA postsynaptic membrane
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000299565 CHRNA5-001 protein_coding Homo_sapiens 0 1275
ENST00000348639 CHRNA3-002 protein_coding Homo_sapiens 8e-27 126
ENST00000394802 CHRNA5-002 protein_coding Homo_sapiens 0 608
ENST00000559002 CHRNA3-004 processed_transcript Homo_sapiens 2e-26 122
ENST00000559554 CHRNA5-003 protein_coding Homo_sapiens 0 436
ENST00000559576 CHRNA5-004 protein_coding Homo_sapiens 0 195
ENST00000559658 CHRNA3-003 nonsense_mediated_decay Homo_sapiens 6e-28 130

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