C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha 5 (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000299565 CHRNA5-001 ENSG00000169684 9606 + 15:78565520-78595269 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartKidneyLiverOvaryPlacentaENST00000299565
Transcript ID Brain Breast Heart Kidney Liver Ovary Placenta
ENST00000299565 0.050±0.00 0.104±0.00 0.027±0.00 0.109±0.00 0.069±0.05 0.028±0.00 0.052±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TW CIL_0003TW_0001 CGP 15:78540405-78595269
CIL_0003TT CIL_0003TT_0001 CGP 15:78565520-78621295

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004889 NAS acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005892 IC acetylcholine-gated channel complex
GO:0006810 NAS:IEA transport
GO:0006811 IEA ion transport
GO:0006812 NAS cation transport
GO:0007165 NAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0015276 TAS ligand-gated ion channel activity
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0035094 IEA response to nicotine
GO:0035095 IMP behavioral response to nicotine
GO:0045211 IEA postsynaptic membrane
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000093844 Chrna5-201 protein_coding Mus_musculus 0 1275

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