C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000108402 Slc6a4-003 ENSMUSG00000020838 10090 + 11:76998603-77032339 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastColonOvaryENSMUST00000108402
Transcript ID Adipose Breast Colon Ovary
ENSMUST00000108402 0.378±0.12 0.358±0.02 1.076±0.00 1.634±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0005335 IEA:ISS serotonin:sodium symporter activity
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0005829 IEA cytosol
GO:0005886 ISS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006837 IMP serotonin transport
GO:0007420 IEA brain development
GO:0007584 IEA response to nutrient
GO:0007613 IEA memory
GO:0007623 IEA circadian rhythm
GO:0008504 ISO monoamine transmembrane transporter activity
GO:0009636 IEA response to toxic substance
GO:0010033 IEA response to organic substance
GO:0010628 IMP positive regulation of gene expression
GO:0012505 ISS endomembrane system
GO:0015222 ISS serotonin transmembrane transporter activity
GO:0015844 ISO monoamine transport
GO:0017022 IEA myosin binding
GO:0017075 IEA syntaxin-1 binding
GO:0017137 IEA Rab GTPase binding
GO:0019811 IEA cocaine binding
GO:0021794 IEA thalamus development
GO:0021941 IEA negative regulation of cerebellar granule cell precursor proliferation
GO:0032227 IEA negative regulation of synaptic transmission, dopaminergic
GO:0032355 IEA response to estradiol
GO:0035176 IGI social behavior
GO:0042310 IEA vasoconstriction
GO:0042493 IEA response to drug
GO:0042713 IEA sperm ejaculation
GO:0042803 IEA protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0045121 IEA membrane raft
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045787 IMP positive regulation of cell cycle
GO:0046621 IMP negative regulation of organ growth
GO:0048854 IMP brain morphogenesis
GO:0050998 IPI nitric-oxide synthase binding
GO:0051015 ISS actin filament binding
GO:0051259 ISS protein oligomerization
GO:0051260 IEA protein homooligomerization
GO:0051610 ISS serotonin uptake
GO:0055085 IEA transmembrane transport
GO:0071300 IEA cellular response to retinoic acid
GO:0071310 IDA cellular response to organic substance
GO:0071321 IEA cellular response to cGMP

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261707 SLC6A4-201 protein_coding Homo_sapiens 0 2429
ENST00000394821 SLC6A4-001 protein_coding Homo_sapiens 0 2198
ENST00000401766 SLC6A4-002 protein_coding Homo_sapiens 0 2429
ENST00000579221 SLC6A4-003 nonsense_mediated_decay Homo_sapiens 0 584

Loading