C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 6 (neurotransmitter transporter), member 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000401766 SLC6A4-002 ENSG00000108576 9606 - 17:30194319-30236002 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000401766
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000401766 0.171±0.00 0.051±0.00 0.090±0.00 0.025±0.00 0.024±0.00 0.046±0.04 0.040±0.02 3.196±1.92 0.051±0.00 0.148±0.04 3.061±0.79

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GG CIL_0004GG_0002 CGP 17:30194319-30292056

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005335 IEA:IMP serotonin:sodium symporter activity
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005887 IEA:IC integral component of plasma membrane
GO:0006836 IEA neurotransmitter transport
GO:0006837 IDA serotonin transport
GO:0008504 IDA monoamine transmembrane transporter activity
GO:0009636 IDA response to toxic substance
GO:0012505 IDA endomembrane system
GO:0015222 IMP serotonin transmembrane transporter activity
GO:0015844 IDA monoamine transport
GO:0016021 IEA integral component of membrane
GO:0017137 IPI Rab GTPase binding
GO:0021794 IMP thalamus development
GO:0035176 ISS social behavior
GO:0045121 IDA membrane raft
GO:0046621 ISS negative regulation of organ growth
GO:0048854 ISS brain morphogenesis
GO:0051015 ISS actin filament binding
GO:0051259 ISS protein oligomerization
GO:0051610 IDA serotonin uptake
GO:0055085 IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021195 Slc6a4-001 protein_coding Mus_musculus 0 2429
ENSMUST00000108402 Slc6a4-003 protein_coding Mus_musculus 0 2429
ENSMUST00000129572 Slc6a4-002 protein_coding Mus_musculus 0 486

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