C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activating transcription factor 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109605 Atf4-201 ENSMUSG00000042406 10090 + 15:80255184-80257540 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000109605
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000109605 79.694±1.15 105.314±29.77 133.505±45.57 94.348±34.20 93.196±6.19 84.040±8.50 34.973±2.89 55.921±9.50 130.122±79.87 83.060±4.42 86.328±14.00 104.648±27.16 118.440±16.56 21.705±4.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003MS CIL_0003MS_0002 CGP 15:80234080-80257540
CIL_0005W7 CIL_0005W7_0002 CGP 15:80255184-80264306

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001077 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006094 IDA gluconeogenesis
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0007623 IEP circadian rhythm
GO:0008022 IEA protein C-terminus binding
GO:0032590 IEA dendrite membrane
GO:0032922 IMP circadian regulation of gene expression
GO:0034399 IEA nuclear periphery
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0036091 IEA positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043005 IEA neuron projection
GO:0043267 IEA negative regulation of potassium ion transport
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1903204 IEA negative regulation of oxidative stress-induced neuron death
GO:1990037 IEA Lewy body core
GO:1990440 IMP positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000337304 ATF4-002 protein_coding Homo_sapiens 0 1299
ENST00000393544 ATF4P4-002 processed_transcript Homo_sapiens 0 1107
ENST00000396680 ATF4-201 protein_coding Homo_sapiens 0 1493
ENST00000404241 ATF4-001 protein_coding Homo_sapiens 0 1489
ENST00000433309 ATF4P3-001 processed_pseudogene Homo_sapiens 0 1129
ENST00000438498 ATF4P4-001 transcribed_processed_pseudogene Homo_sapiens 0 1088
ENST00000443279 ATF4P1-001 processed_pseudogene Homo_sapiens 0 523
ENST00000601944 ATF4P1-001 processed_pseudogene Homo_sapiens 0 523

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